Association of ADHD, tics, and anxiety with dopamine transporter (DAT1) genotype in autism spectrum disorder
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چکیده
منابع مشابه
Association of COMT (Val158Met) and BDNF (Val66Met) gene polymorphisms with anxiety, ADHD and tics in children with autism spectrum disorder.
The aim of the study is to examine rs4680 (COMT) and rs6265 (BDNF) as genetic markers of anxiety, ADHD, and tics. Parents and teachers completed a DSM-IV-referenced rating scale for a total sample of 67 children with autism spectrum disorder (ASD). Both COMT (p = 0.06) and BDNF (p = 0.07) genotypes were marginally significant for teacher ratings of social phobia (etap (2) = 0.06). Analyses also...
متن کاملAssociation of the dopamine transporter (SLC6A3/DAT1) gene 9-6 haplotype with adult ADHD.
ADHD is a neuropsychiatric disorder characterized by chronic hyperactivity, inattention and impulsivity, which affects about 5% of school-age children. ADHD persists into adulthood in at least 15% of cases. It is highly heritable and familial influences seem strongest for ADHD persisting into adulthood. However, most of the genetic research in ADHD has been carried out in children with the diso...
متن کاملAssociation of dopamine gene variants, emotion dysregulation and ADHD in autism spectrum disorder.
The aim of the present study was to evaluate the association of dopaminergic gene variants with emotion dysregulation (EMD) and attention-deficit/hyperactivity disorder (ADHD) symptoms in children with autism spectrum disorder (ASD). Three dopamine transporter gene (SLC6A3/DAT1) polymorphisms (intron8 5/6 VNTR, 3'-UTR 9/10 VNTR, rs27072 in the 3'-UTR) and one dopamine D2 receptor gene (DRD2) va...
متن کاملComparison of Motor Skills in At-risk with Autism Spectrum Disorder Children with Autism Spectrum Disorder and Typical Development Children
Background: Autism Spectrum Disorder (ASD) is a complex developmental disorder characterized by repetitive and stereotypical patterns, and difficulties with social communication and interaction in early childhood. Motor development and dysfunction in children with ASD has been the subject of study in recent years and has attracted much of the attention of researchers. As motor dysfunctions can ...
متن کاملComparison of anxiety symptoms in preschoolers with and without autism spectrum disorder
Introduction: Anxiety symptoms have been reported in children with autism. However, most studies have focused on school-aged children and early anxiety symptoms in preschoolers with autism and their comparison in groups of children with different symptom severity and normal children have been less addressed. So, this study sought to compare total anxiety and anxiety symptoms in children with mi...
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ژورنال
عنوان ژورنال: Journal of Child Psychology and Psychiatry
سال: 2008
ISSN: 0021-9630,1469-7610
DOI: 10.1111/j.1469-7610.2008.01952.x